Fatty Acids in Habitual Diet, Plasma Phospholipids, and Tumour and Normal Colonic Biopsies in Young Colorectal Cancer Patients
نویسندگان
چکیده
منابع مشابه
Fatty Acids in Habitual Diet, Plasma Phospholipids, and Tumour and Normal Colonic Biopsies in Young Colorectal Cancer Patients
Fatty acid metabolism is altered in colorectal cancer (CRC). We aimed to investigate incorporation of dietary n-6 and n-3 polyunsaturated fatty acids (PUFAs) into plasma phospholipids (PLs), tumour tissue, and normal mucosa in young CRC patients. We also aimed to study differences in PUFA composition between tumour and normal mucosa, and PUFA status associated with cancer stage. Sixty-five CRC ...
متن کاملAbnormalities in fatty acids in plasma, erythrocytes and adipose tissue in Japanese patients with colorectal cancer.
AIM In previous animal studies, we confirmed that linoleic acid (LNA) enhanced colon carcinogenesis, whereas eicosapentaenoic acid (EPA) had protective effects in azoxymethane-induced colon tumorigenesis. In regard to the protective effects of marine n-3 polyunsaturated fatty acids (PUFAs) on colorectal cancer however, evidence from epidemiological studies is inconsistent. MATERIALS AND METHO...
متن کاملLong-chain polyunsaturated fatty acids profile in plasma phospholipids of hyperphenylalaninemic children on unrestricted diet.
INTRODUCTION The aim of the present study was to examine whether hyperphenylalaninemic children on unrestricted diet (MHP) may exhibit a different LCPUFA profile from PKU or healthy children in plasma phospholipids. PATIENTS AND METHODS Forty-five MHP children (age 9-14 years) were age and sex matched with 45 PKU and 45 healthy children. Fatty acids were determined and expressed as % of total...
متن کاملCTGF and MLH1 Gene Expression Levels in Colorectal Cancer Tumor Tissues and Adjacent Normal Tissues in Patients in Golestan Province
Background and purpose: Colorectal cancer is the third most common type of cancer in terms of incidence and the second most common cause of cancer-related death worldwide. The aim of this study was to investigate the expression of CTGF and MLH1 gene in colorectal cancer tumor tissues and adjacent normal tissues in patients in Golestan province. Materials and methods: In this experimental study...
متن کاملInteraction of Fatty Acid Genotype and Diet on Changes in Colonic Fatty Acids in a
Mediterranean Diet Intervention Study 2 3 Shannon R. Porenta, Yi-An Ko, Stephen B. Gruber*, 4 Bhramar Mukherjee, Ana Baylin, Jianwei Ren, and Zora Djuric 5 6 a Departments of Internal Medicine, b Biostatistics, c Epidemiology, and d Family Medicine 7 University of Michigan, Ann Arbor, MI 48109 8 *Present address: University of Southern California, Norris Comprehensive Cancer Center, 9 Keck Scho...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Journal of Oncology
سال: 2012
ISSN: 1687-8450,1687-8469
DOI: 10.1155/2012/254801